General Information

  • ID:  hor002767
  • Uniprot ID:  A0A0L0CC22
  • Protein name:  PQNa
  • Gene name:  NA
  • Organism:  Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Lucilia (genus), Luciliinae (subfamily), Calliphoridae (family), Oestroidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  NIGTLARDFQLPQN
  • Length:  14(175-188)
  • Propeptide:  MPPVNNNNKKNLHPLAVIKLCVLFGMLLNVLQHPRAVKATDDVANVSPCELESIINQLVYPSPQYQMHAASLRNQLRNILRERQLEEGEEQSLNNDMDYLEEDKRSVAALAAQGLLHHNNNAAAAKRSLATLAKNGQLPTPDPEIMPDGDQRSEDKRYVGALARSGGLMGYGKRNIGTLARDFQLPQNGKRNLATMARLGMLGNRNDPKRNLASVARYNSRMYNNAAEKRNIGALKGSPVHGGVQMKRSEDDVYL
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A0L0CC22-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002767_AF2.pdbhor002767_ESM.pdb

Physical Information

Mass: 181884 Formula: C69H111N21O22
Absent amino acids: CEHKMSVWY Common amino acids: LNQ
pI: 6.34 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 5
Hydrophobicity: -57.14 Boman Index: -3008
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 90.71
Instability Index: 5673.57 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  23280433
  • Title:  Neuropeptidomics of the Australian Sheep Blowfly Lucilia Cuprina (Wiedemann) and Related Diptera